Efficacy of High-Flow Nasal Oxygen Therapy in Adult Intensive Care Units: a Comprehensive Review and Meta-Analysis

EasyChair Preprint 13677

Abstract

High-flow nasal oxygen (HFNO) therapy has emerged as a promising non-invasive respiratory support modality, particularly in adult intensive care units (ICUs). This comprehensive review and meta-analysis aim to evaluate the efficacy of HFNO therapy in adult ICU patients, assessing its impact on clinical outcomes, including respiratory parameters, patient comfort, and overall mortality. Data from randomized controlled trials (RCTs) and observational studies were systematically analyzed to compare HFNO with conventional oxygen therapy and other non-invasive ventilation methods. Our findings indicate that HFNO significantly improves oxygenation, reduces the need for intubation, and enhances patient comfort compared to standard oxygen therapy. Additionally, HFNO was associated with lower ICU mortality rates and fewer adverse events. This review highlights the clinical advantages of HFNO, advocating for its broader implementation in adult ICUs to optimize respiratory care and patient outcomes. Further research is recommended to refine patient selection criteria and establish standardized protocols for HFNO therapy in diverse ICU settings.

Keyphrases: High-flow nasal oxygen (HFNO), Intensive Care Units (ICUs), randomized controlled trials (RCTs)

@booklet{EasyChair:13677,
  author    = {Abill Robert},
  title     = {Efficacy of High-Flow Nasal Oxygen Therapy in Adult Intensive Care Units: a Comprehensive Review and Meta-Analysis},
  howpublished = {EasyChair Preprint 13677},
  year      = {EasyChair, 2024}}