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Precision in Inhibition: Decoding Structural Signatures in Hsp90 Alpha for Advanced Cancer Therapeutics

EasyChair Preprint 11674

6 pagesDate: January 3, 2024

Abstract

Cancer treatment has witnessed significant advancements with the emergence of targeted therapies, among which inhibitors of the Heat Shock Protein 90 (Hsp90) alpha isoform have shown promising results. This study focuses on the meticulous exploration of structural signatures within Hsp90 alpha inhibitors, aiming to unveil the key determinants contributing to their advanced efficacy in cancer therapeutics. Through a comprehensive analysis of molecular structures and binding interactions, we decipher the intricate code governing the precision of Hsp90 alpha inhibition. Utilizing state-of-the-art computational methods, we identify specific structural motifs and binding pockets crucial for optimal therapeutic outcomes. The decoding of these structural signatures provides insights into the nuanced mechanisms underlying the effectiveness of Hsp90 alpha inhibitors, enabling the design of next-generation precision therapies.

Keyphrases: Anticancer, development, drug

BibTeX entry
BibTeX does not have the right entry for preprints. This is a hack for producing the correct reference:
@booklet{EasyChair:11674,
  author    = {Kurez Oroy and Herber Schield},
  title     = {Precision in Inhibition: Decoding Structural Signatures in Hsp90 Alpha for Advanced Cancer Therapeutics},
  howpublished = {EasyChair Preprint 11674},
  year      = {EasyChair, 2024}}
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