Sorption of Human Serum Albumin on Surface IPN Acrylic Hydrogels Filled with Sodium Hyaluronate

EasyChair Preprint 1877

Abstract

In this work, IPN hydrogels based on a copolymer of acrylic acid and acrylamide filled with various amounts of sodium hyaluronate and bentonite were synthesized. For these hydrogels, the sorption capacity in relation to human serum albumin was studied, because protein sorption is one of the most important stages of cell adhesion. Shown, that due to an increase in the concentration of additional charged carboxylate groups, an increase in sorption capacity to 0.35 g of albumin per 1 g of hydrogel is observed with an increase in the percentage of sodium hyaluronate. With an increase in the proportion of benonite in the hydrogel composite, the sorption capacity for IPN gels filled with 0.05mas.% sodium hyaluronate also increases from 0.27 g to 0.38 g per 1 g of hydrogel.

Keyphrases: Bentonite, Hydrogels, human serum albumin, radical polimerisation, sodium hyaluronat, sorption

@booklet{EasyChair:1877,
  author    = {Tatiana Nosenko and Vera Sitnikova and Maya Uspenskaya},
  title     = {Sorption of Human Serum Albumin on Surface IPN Acrylic Hydrogels Filled with Sodium Hyaluronate},
  howpublished = {EasyChair Preprint 1877},
  year      = {EasyChair, 2019}}