Heat Transfer Analysis in Human Skin During Hyperthermia Treatment Using Dual Phase Lag Model: a Finite Difference Approach

EasyChair Preprint 7295

Abstract

The present work focuses on the temperature distribution through the skin layer when the outer layer of the human skin surface is directly subjected to a sinusoidal heat flux to cure tumour cells located inside the body. The process of the treatment is known as local hyperthermia treatment. A mathematical model is developed to investigate the effect of phase lag due to thermal inertia and microstructural interaction. Spatial variation of temperature has numerically been calculated using Dual Phase Lag Model for Bio-Heat Transfer (DPLMBHT). Besides, blood perfusion rate, heat generation due to metabolism, and heat absorption in the skin layer has been analysed. Also, the effects of both phase lags are discussed, and the wave nature of heat propagation has been observed. It has been found that phase lag due to microstructural interaction has not much effect on the degree of slowness of heat propagation through the living tissue than the phase lag due to thermal inertia. Phase lag due to temperature gradient diffuses the heat ahead of the wave front of the heat propagation due to phase lag due to heat flux. It is also observed that the temperature variation decreases with the increase of frequency, which is essential for hyperthermia treatment to maintain a constant temperature at any particular position in the human body for a necessary period.

Keyphrases: Dual-phase lag bioheat transfer, Thermal relaxation time, finite difference method

@booklet{EasyChair:7295,
  author    = {Aishik Dinda and Jnanaranjan Acharya and Dipankar Bhanja},
  title     = {Heat Transfer Analysis in Human Skin During Hyperthermia Treatment Using Dual Phase Lag Model: a Finite Difference Approach},
  howpublished = {EasyChair Preprint 7295},
  year      = {EasyChair, 2022}}